Retinol and Peptide Face Serum
The two ingredients with the strongest anti-aging evidence, retinol and a collagen-signal peptide, in one nightly serum.
Renewal from two directions
Retinol is vitamin A. It speeds the rate at which skin cells turn over and signals fibroblasts, the cells that build collagen, to get back to work, which is why decades of trials tie it to smoother texture and softer lines. Palmitoyl pentapeptide works by a different route: it is a short protein fragment that acts like a message telling skin to make more collagen and elastin. Using both at night hits skin renewal from two angles. Retinol can dry or flake at first, so this serum is buffered with humectants and is meant to be introduced slowly.
Sun and years both show up on the face
Time outdoors is time under UV, and UV is the single biggest driver of lines, rough texture and loss of firmness. Retinol is the best-evidenced way to work against that at home, and the peptide gives collagen a second nudge. Use it at night, when skin repairs, and treat daily sunscreen as non-negotiable, retinol makes skin more sun-sensitive. It will not undo a decade in a week, but over months it is the most reliable anti-aging step there is.
Studied, not just marketed
Retinol and signal peptides are two of the few anti-aging ingredients with real controlled-trial evidence. Here is what is published.
Summaries describe published research on the ingredient, not on this specific product. Individual results vary.
The one evening step worth keeping
If you want to look less tired and less aged under boardroom and camera light, the highest-return move is not a new gadget, it is retinol at night, used consistently. This pairs it with a collagen-signal peptide and enough hydration that you can actually tolerate it. Two or three nights a week to start, then most nights. It asks for patience and a morning sunscreen, and it pays that back as skin that looks smoother and firmer over a few months.
Why Dr. Elizabeth stocks this
"Retinol is the one anti-aging ingredient I would keep if I could keep only one, and the peptide is a gentle multiplier on top of it. The mistake almost everyone makes is going too hard too fast and quitting when their skin flakes. Start two nights a week, moisturise over the top, never skip morning sunscreen, and give it three months before you judge it."
What to expect
Patch-test, then apply a pea-sized amount to dry skin 2 to 3 nights a week, moisturiser on top. A little dryness or flaking early on is normal; redness that lasts is not.
As your skin adjusts, build toward most nights. Texture starts to look smoother and more even in this window.*
Collagen change is slow. Fine lines and firmness improve with continued nightly use and daily SPF; this is a keep-going habit.
The details
Ingredients, suggested use & label facts
Our Retinol and Peptide Face Serum is crafted to refine and refresh the skin’s appearance overnight. Retinol, known for its smoothing properties, works together with peptides to support the look of skin firmness and texture. The result is a complexion that appears more even and polished over time.
Soothing ingredients like bisabolol and nourishing phospholipids help support a soft, balanced feel, complementing the refining benefits of retinol. Its lightweight, silky texture absorbs quickly without feeling heavy.
Use nightly after cleansing by applying 3–4 drops to the face and neck. Follow with moisturizer, and remember to use sunscreen during the day, as retinol may increase skin sensitivity to sunlight.
Ingredients: Aqua (Water), Caprylic/Capric Triglyceride, Phospholipids, Retinol, Aluminum Starch Octenylsuccinate, 1,2-Hexanediol, Butylene Glycol, Propanediol, Hexapeptide-11, Ammonium Acryloyldimethyltaurate/Carboxyethyl Acrylate Crosspolymer, Sodium Polyacrylate, Bisabolol.
Manufacturer's country: USA
Product amount (oz/lbs/ml): 1 fl oz / 0.07 lbs / 30 ml
Gross weight (oz/lbs/g): 2.7 oz / 0.17 lbs / 77 g
Suggested use: After cleansing, use fingers to apply 3-4 drops of serum to face and neck at night. Use sunscreen the morning after you apply.
Warning: If pregnant or nursing, consult your physician before use. For external use only. Avoid contact with eyes. If irritation occurs, discontinue use. Shake well before use.

Quality & testing
Made in the USA in a GMP-compliant, FDA-registered facility. A Certificate of Analysis is available for every product on request, email us and we will send it. Nothing on this shelf is stocked until Dr. Elizabeth has reviewed the formula and its label.
Shipping & returns
Orders ship from the USA within 1-3 business days. Free shipping on orders over $100. If a formula is not working for you, email us within 30 days of delivery for a refund, see our refund policy for details.
Good questions
How often should I use it?
Start with 2 to 3 nights a week to let your skin adjust, then build toward nightly. More is not better with retinol; consistency is.
Is some flaking normal?
Light dryness or flaking in the first few weeks is common as skin adjusts. Buffer by applying moisturiser first or after. Stop if you get persistent redness, burning or swelling.
Can I use it while pregnant or nursing?
No. Avoid retinol and other retinoids during pregnancy and breastfeeding; speak to your physician about alternatives.
Morning or night?
Night only. Retinol degrades in sunlight and makes skin more sun-sensitive, so it belongs in your PM routine, always followed by morning sunscreen.
Can I use it with vitamin C or acids?
Use vitamin C in the morning and retinol at night. Go easy combining retinol with strong exfoliating acids; alternate nights if your skin is sensitive.
Pairs well with