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Retinol and Peptide Face Serum
Facial Care

Retinol and Peptide Face Serum

The two ingredients with the strongest anti-aging evidence, retinol and a collagen-signal peptide, in one nightly serum.

Retinolvitamin A, the gold standard
Peptidepalmitoyl signal peptide
30 ml1 fl oz dropper
PMnightly, build up slowly
Softens the look of fine lines, wrinkles and rough texture over time*
Retinol, the most studied anti-aging ingredient in dermatology
A signal peptide that nudges the skin's own collagen-making cells
Buffered with hydration to ease the dryness retinol can cause
1
Made in USA
GMP-compliant facility
FDA-registered facility
ALCOHOL FREE
CRUELTY FREE
FRAGRANCE FREE
MADE IN USA
MINERAL OIL FREE
PARABEN FREE
PHTHALATE FREE
SULFATE FREE
VEGAN
VEGETARIAN
Free shipping over $100 · 30-day money-back guarantee
For external use only. Introduce slowly, 2 to 3 nights a week to start. Patch-test before first use; discontinue if irritation occurs. Use sunscreen daily; retinol increases sun sensitivity.
Why it works

Renewal from two directions

Retinol is vitamin A. It speeds the rate at which skin cells turn over and signals fibroblasts, the cells that build collagen, to get back to work, which is why decades of trials tie it to smoother texture and softer lines. Palmitoyl pentapeptide works by a different route: it is a short protein fragment that acts like a message telling skin to make more collagen and elastin. Using both at night hits skin renewal from two angles. Retinol can dry or flake at first, so this serum is buffered with humectants and is meant to be introduced slowly.

Renewal from two directions
For athletes

Sun and years both show up on the face

Time outdoors is time under UV, and UV is the single biggest driver of lines, rough texture and loss of firmness. Retinol is the best-evidenced way to work against that at home, and the peptide gives collagen a second nudge. Use it at night, when skin repairs, and treat daily sunscreen as non-negotiable, retinol makes skin more sun-sensitive. It will not undo a decade in a week, but over months it is the most reliable anti-aging step there is.

Sun and years both show up on the face
What the research shows

Studied, not just marketed

Retinol and signal peptides are two of the few anti-aging ingredients with real controlled-trial evidence. Here is what is published.

Randomized, vehicle-controlled trial
Retinol
In adults with naturally aged skin, applying retinol lotion three times a week for 24 weeks significantly reduced fine wrinkles compared with the vehicle, and increased skin's collagen-related activity.
Double-blind, placebo-controlled trial
Peptide
Topical palmitoyl pentapeptide applied for 12 weeks improved the appearance of photoaged facial skin, including wrinkles and skin texture, compared with placebo.

Summaries describe published research on the ingredient, not on this specific product. Individual results vary.

For faces that are always on

The one evening step worth keeping

If you want to look less tired and less aged under boardroom and camera light, the highest-return move is not a new gadget, it is retinol at night, used consistently. This pairs it with a collagen-signal peptide and enough hydration that you can actually tolerate it. Two or three nights a week to start, then most nights. It asks for patience and a morning sunscreen, and it pays that back as skin that looks smoother and firmer over a few months.

The one evening step worth keeping
From the physician

Why Dr. Elizabeth stocks this

"Retinol is the one anti-aging ingredient I would keep if I could keep only one, and the peptide is a gentle multiplier on top of it. The mistake almost everyone makes is going too hard too fast and quitting when their skin flakes. Start two nights a week, moisturise over the top, never skip morning sunscreen, and give it three months before you judge it."

Why Dr. Elizabeth stocks this

What to expect

Weeks 1-2

Patch-test, then apply a pea-sized amount to dry skin 2 to 3 nights a week, moisturiser on top. A little dryness or flaking early on is normal; redness that lasts is not.

Weeks 4-8

As your skin adjusts, build toward most nights. Texture starts to look smoother and more even in this window.*

Week 12+

Collagen change is slow. Fine lines and firmness improve with continued nightly use and daily SPF; this is a keep-going habit.

Individual results vary. Consistency matters more than intensity.

The details

Ingredients, suggested use & label facts

Our Retinol and Peptide Face Serum is crafted to refine and refresh the skin’s appearance overnight. Retinol, known for its smoothing properties, works together with peptides to support the look of skin firmness and texture. The result is a complexion that appears more even and polished over time.


Soothing ingredients like bisabolol and nourishing phospholipids help support a soft, balanced feel, complementing the refining benefits of retinol. Its lightweight, silky texture absorbs quickly without feeling heavy.


Use nightly after cleansing by applying 3–4 drops to the face and neck. Follow with moisturizer, and remember to use sunscreen during the day, as retinol may increase skin sensitivity to sunlight.


Ingredients: Aqua (Water), Caprylic/Capric Triglyceride, Phospholipids, Retinol, Aluminum Starch Octenylsuccinate, 1,2-Hexanediol, Butylene Glycol, Propanediol, Hexapeptide-11, Ammonium Acryloyldimethyltaurate/Carboxyethyl Acrylate Crosspolymer, Sodium Polyacrylate, Bisabolol.

Manufacturer's country: USA

Product amount (oz/lbs/ml): 1 fl oz / 0.07 lbs / 30 ml

Gross weight (oz/lbs/g): 2.7 oz / 0.17 lbs / 77 g

Suggested use: After cleansing, use fingers to apply 3-4 drops of serum to face and neck at night. Use sunscreen the morning after you apply.

Warning: If pregnant or nursing, consult your physician before use. For external use only. Avoid contact with eyes. If irritation occurs, discontinue use. Shake well before use.

Vegetarian Vegan friendly Alcohol Free Cruelty Free Fragrance Free Mineral Oil Free Paraben Free Phthalate Free Sulfate Free

Quality & testing

Made in the USA in a GMP-compliant, FDA-registered facility. A Certificate of Analysis is available for every product on request, email us and we will send it. Nothing on this shelf is stocked until Dr. Elizabeth has reviewed the formula and its label.

Shipping & returns

Orders ship from the USA within 1-3 business days. Free shipping on orders over $100. If a formula is not working for you, email us within 30 days of delivery for a refund, see our refund policy for details.

Good questions

How often should I use it?

Start with 2 to 3 nights a week to let your skin adjust, then build toward nightly. More is not better with retinol; consistency is.

Is some flaking normal?

Light dryness or flaking in the first few weeks is common as skin adjusts. Buffer by applying moisturiser first or after. Stop if you get persistent redness, burning or swelling.

Can I use it while pregnant or nursing?

No. Avoid retinol and other retinoids during pregnancy and breastfeeding; speak to your physician about alternatives.

Morning or night?

Night only. Retinol degrades in sunlight and makes skin more sun-sensitive, so it belongs in your PM routine, always followed by morning sunscreen.

Can I use it with vitamin C or acids?

Use vitamin C in the morning and retinol at night. Go easy combining retinol with strong exfoliating acids; alternate nights if your skin is sensitive.

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