Magnesium Glycinate
For the 6 a.m. athlete and the 11 p.m. executive: the well-absorbed form of the mineral hard training and hard days drain first — dosed the way the sleep research dosed it.*
The mineral that quietly runs 300 reactions
Magnesium sits inside more than 300 enzyme systems — energy production, nerve signalling, muscle contraction, and the pathway that lets your body wind down at night. Surveys consistently show that a large share of American adults fall short of the recommended intake from food alone. Glycinate is magnesium bound to the amino acid glycine: it is absorbed well, rarely causes the digestive upset cheaper forms do, and glycine itself has a calming reputation of its own.*
You lose it in sweat. Then you lose sleep over it.
Hard training raises your magnesium requirement and drains it through sweat and urine — and the more you train, the wider the gap. Magnesium sits inside the machinery that contracts and relaxes muscle, clears lactate and lets your nervous system switch from fight to rest. When it runs short, the signs are the ones athletes know too well: heavy legs that won't loosen, cramps at 2 a.m., wired-but-tired nights after evening sessions. Three capsules of glycinate with dinner top up what the session took out, without the stomach issues of citrate or oxide — and the sleep that follows is where adaptation actually happens.*
Studied, not just marketed
The effect of magnesium on sleep is real but modest, and it is largest in people who were low to begin with — which, if you train hard or run a company, is very likely you. We would rather tell you that than oversell it.
Summaries describe published research on the ingredient, not on this specific product. Individual results vary. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Stress burns magnesium. Low magnesium makes stress worse.
Researchers call it the vicious circle: psychological stress increases the body's loss of magnesium, and low magnesium makes the stress response louder — higher cortisol, lighter sleep, a mind that keeps running after the laptop closes. If your calendar looks like a flight schedule, the mineral you are most likely to be short of is this one. A systematic review of supplementation trials found magnesium supported subjective measures of stress in people who were low or under strain to begin with.* This is not a sedative and it will not slow you down the next morning. It simply gives the off-switch what it needs to work.*
Why Dr. Elizabeth stocks this
"Poor sleep, tight muscles, afternoon fatigue — magnesium status is one of the first things I look at, and glycinate is the form I actually use in the exam room. 275 mg of elemental magnesium puts you in the range the sleep trials tested, in three small capsules that don't upset the stomach. It is the simplest, most boring fix on this shelf, and boring fixes are the ones people stick with."
What to expect
Take three capsules with your evening meal. Many people notice a calmer wind-down in the first week; digestion should stay comfortable — that is the point of glycinate.
This is the window the clinical trials measured. Expect the change to show up as easier sleep onset and fewer restless nights rather than a dramatic knockout.*
Magnesium stores build slowly. Keep going; pair it with a consistent bedtime and the benefits compound.*
The details
Ingredients, suggested use & label facts
Magnesium Glycinate delivers 275 mg of elemental magnesium per serving, from 2,500 mg of magnesium bisglycinate — the chelated form chosen for absorption and comfort. Magnesium is required by more than 300 enzyme systems, including those behind muscle relaxation, nerve signalling, energy production and the body's natural wind-down at night.*
Selected by Dr. Elizabeth Isalguez, MD, for the patients of her Miami internal and functional medicine practice, and now available to you. Three small vegetarian capsules, taken with your evening meal.
- Supports restful sleep and a calm nervous system*
- Supports muscle relaxation and recovery*
- Glycinate form — gentle on digestion
- Vegan-friendly capsule, non-GMO, gluten-free
Gluten-free · Vegetarian · Vegan-friendly · Non-GMO · Lactose-free · Corn-free · Hormone-free · Antibiotic-free
Ingredients: Magnesium (from 2,500 mg Magnesium Glycinate) 275 mg, Hypromellose (capsule), Magnesium Stearate, Silicon Dioxide, Rice Flour.
Amount: 90 capsules (30 servings)
Suggested use: As a dietary supplement, take three (3) capsules once daily or as directed by your healthcare professional.
Caution: Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Warning: Keep out of reach of children. Do not use if the safety seal is damaged or missing. Store in a cool, dry place.
Made in: USA
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Quality & testing
Made in the USA in a GMP-compliant, FDA-registered facility. A Certificate of Analysis is available for every product on request — email us and we will send it. Nothing on this shelf is stocked until Dr. Elizabeth has reviewed the formula and its label.
Shipping & returns
Orders ship from the USA within 1–3 business days. Free shipping on orders over $100. If a formula is not working for you, email us within 30 days of delivery for a refund — see our refund policy for details.
Good questions
Why glycinate and not oxide or citrate?
Magnesium oxide is poorly absorbed and citrate is a known laxative. Glycinate (bisglycinate) is bound to the amino acid glycine, which improves absorption and is gentle on the stomach — the reason it is the form most often used for evening routines.
I train in the evening — when do I take it?
After the session, with your post-workout meal or dinner. Magnesium is part of what lets muscle relax and the nervous system downshift after hard work; taking it then supports both recovery and the sleep that follows.
Does it help with jet lag or travel sleep?
It is not a sedative and will not knock you out on a plane. What it does is support the body's own wind-down and muscle relaxation, which frequent travellers often find makes unfamiliar beds and shifted bedtimes easier. Take it with your evening meal in the new time zone.
When should I take it?
With your evening meal, or 1–2 hours before bed. Consistency matters more than exact timing.
Is 275 mg a lot?
No. The daily recommended intake for adults is 310–420 mg and most of that should still come from food. 275 mg tops up a typical shortfall; the tolerable upper limit for supplemental magnesium is 350 mg per day.
Can I take it with other supplements?
Magnesium pairs well with Omega-3 and CoQ10. Separate it from high-dose zinc or calcium by a couple of hours. If you take prescription medication — especially for blood pressure, antibiotics or bisphosphonates — check with your physician first.
Who should not take it?
People with kidney disease, anyone pregnant or nursing, and anyone under 18 should talk to a physician before starting.

